The Natarajan Lab is equipped with state of the art infrastructure to support the discovery and development of next-generation therapeutics.

Please contact us (med.chemistry@ucmail.uc.edu) for the following:

• Computational chemistry support for structure guided hit-to-lead optimization studies

• Focused chemical libraries to conduct hit-to-lead optimization studies

• Scale up of compounds (mg to grams) for in vivo studies to demonstrate proof of concept

• Small molecules that are not commercially available (including compounds found in patents) for interrogating novel biological targets / pathways

• Structurally validated small molecules identified from HTS campaigns for follow up studies

• Chemical tools (photo-cross-linkable & clickable or fluorescently labeled or biotinylated compounds) to develop assays and / or identify potential biological targets